{"id":90,"date":"2024-10-30T17:39:48","date_gmt":"2024-10-30T16:39:48","guid":{"rendered":"http:\/\/wwww.icp.universite-paris-saclay.fr\/capri\/?page_id=90"},"modified":"2024-11-19T16:30:08","modified_gmt":"2024-11-19T15:30:08","slug":"microfluidics","status":"publish","type":"page","link":"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/en\/equipment\/microfluidics\/","title":{"rendered":"Microfluidics"},"content":{"rendered":"<div id=\"pl-90\"  class=\"panel-layout\" ><div id=\"pg-90-0\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-90-0-0\"  class=\"panel-grid-cell\" ><div id=\"panel-90-0-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" data-index=\"0\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t><h3 class=\"widget-title\">Microfluidics<\/h3>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>Microfluidics, which enables the manipulation of very small quantities of liquid within microvolumes, plays an important role in many activities developed by the CAPRI group. The various applications created within this framework rely on optimized techniques, involving:<\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li>Optical microscopy, coupled with various light sources and imaging detectors, some of which are optimized for UV light<\/li>\n<li>High voltage management within microvolumes<\/li>\n<li>Pressure control and associated connectivity<\/li>\n<li>Additive printing of microfluidic prototypes and replication of chips through pressing techniques<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>All the necessary equipment for these different stages is grouped in two development spaces dedicated to microfluidics.<\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-90-0-1\"  class=\"panel-grid-cell\" ><div id=\"panel-90-0-1-0\" class=\"so-panel widget widget_sow-image panel-first-child\" data-index=\"1\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-image so-widget-sow-image-default-c67d20f9f743-90\"\n\t\t\t\n\t\t>\n<div class=\"sow-image-container\">\n\t\t<img \n\tsrc=\"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-1.jpg\" width=\"2279\" height=\"1516\" srcset=\"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-1.jpg 2279w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-1-300x200.jpg 300w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-1-1024x681.jpg 1024w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-1-768x511.jpg 768w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-1-1536x1022.jpg 1536w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-1-2048x1362.jpg 2048w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-1-930x620.jpg 930w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-1-272x182.jpg 272w\" sizes=\"(max-width: 2279px) 100vw, 2279px\" title=\"MicroF 1\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n\t<\/div>\n\n<\/div><\/div><div id=\"panel-90-0-1-1\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"2\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p style=\"text-align: center;\"><em>3D-printed laboratory model (prototype) for cerebrospinal fluid analysis with detection in microfluidic chips and fluorescence emission in the UV range.<\/em><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-90-1\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-90-1-0\"  class=\"panel-grid-cell\" ><div id=\"panel-90-1-0-0\" class=\"so-panel widget widget_sow-image panel-first-child\" data-index=\"3\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-image so-widget-sow-image-default-c67d20f9f743-90\"\n\t\t\t\n\t\t>\n<div class=\"sow-image-container\">\n\t\t<img \n\tsrc=\"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-2.jpg\" width=\"2279\" height=\"1511\" srcset=\"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-2.jpg 2279w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-2-300x199.jpg 300w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-2-1024x679.jpg 1024w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-2-768x509.jpg 768w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-2-1536x1018.jpg 1536w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-2-2048x1358.jpg 2048w\" sizes=\"(max-width: 2279px) 100vw, 2279px\" title=\"MicroF 2\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n\t<\/div>\n\n<\/div><\/div><div id=\"panel-90-1-0-1\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"4\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p style=\"text-align: center;\"><em>Microfluidic analysis setup with electrophoretic separation, based on an epi-fluorescence optical stand (visible range). The entire instrument is computer-interfaced.<\/em><\/p>\n<\/div>\n<\/div><\/div><\/div><div id=\"pgc-90-1-1\"  class=\"panel-grid-cell\" ><div id=\"panel-90-1-1-0\" class=\"so-panel widget widget_sow-image panel-first-child\" data-index=\"5\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-image so-widget-sow-image-default-c67d20f9f743-90\"\n\t\t\t\n\t\t>\n<div class=\"sow-image-container\">\n\t\t<img \n\tsrc=\"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-3.jpg\" width=\"2279\" height=\"1511\" srcset=\"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-3.jpg 2279w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-3-300x199.jpg 300w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-3-1024x679.jpg 1024w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-3-768x509.jpg 768w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-3-1536x1018.jpg 1536w, https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-content\/uploads\/sites\/2\/2024\/10\/MicroF-3-2048x1358.jpg 2048w\" sizes=\"(max-width: 2279px) 100vw, 2279px\" title=\"MicroF 3\" alt=\"\" \t\tclass=\"so-widget-image\"\/>\n\t<\/div>\n\n<\/div><\/div><div id=\"panel-90-1-1-1\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"6\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p style=\"text-align: center;\"><em>Microfluidic analysis setup using an epi-fluorescence optical stand (visible range) with light polarization modulation.<\/em><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><div id=\"pg-90-2\"  class=\"panel-grid panel-no-style\" ><div id=\"pgc-90-2-0\"  class=\"panel-grid-cell\" ><div id=\"panel-90-2-0-0\" class=\"so-panel widget widget_sow-editor panel-first-child\" data-index=\"7\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p>Among the practical applications carried out are:<\/p>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li>Upstream coupling to mass spectrometer sources, enabling the purification and selective elution of sample of proteins in micro-volumes, such as alpha-synuclein or membrane proteins<\/li>\n<li>Development of a functional prototype of the NanoCODE analysis instrument for the identification of biomarkers in cerebrospinal fluid<\/li>\n<li>Development of micro-plasma coupled to an FTICR mass spectrometer for the analysis of chemical processes occurring within the discharge<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/div>\n<\/div><\/div><div id=\"panel-90-2-0-1\" class=\"so-panel widget widget_sow-editor panel-last-child\" data-index=\"8\" ><div class=\"panel-widget-style panel-widget-style-for-90-2-0-1\" ><div\n\t\t\t\n\t\t\tclass=\"so-widget-sow-editor so-widget-sow-editor-base\"\n\t\t\t\n\t\t><h3 class=\"widget-title\">Contact<\/h3>\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><a href=\"https:\/\/www.icp.universite-paris-saclay.fr\/contact-ap\/\" target=\"_blank\" rel=\"noopener\">Antoine Pallandre<\/a><\/p>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Microfluidics, which enables the manipulation of very small quantities of liquid within microvolumes, plays an important role in many activities developed by the CAPRI group. The various applications created within this framework rely on optimized techniques, involving: Optical microscopy, coupled with various light sources and imaging detectors, some of which are optimized for UV light&hellip;&nbsp;<a href=\"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/en\/equipment\/microfluidics\/\" rel=\"bookmark\">Lire la suite &raquo;<span class=\"screen-reader-text\">Microfluidics<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":62,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"off","neve_meta_content_width":100,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","footnotes":""},"class_list":["post-90","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-json\/wp\/v2\/pages\/90","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-json\/wp\/v2\/comments?post=90"}],"version-history":[{"count":3,"href":"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-json\/wp\/v2\/pages\/90\/revisions"}],"predecessor-version":[{"id":333,"href":"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-json\/wp\/v2\/pages\/90\/revisions\/333"}],"up":[{"embeddable":true,"href":"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-json\/wp\/v2\/pages\/62"}],"wp:attachment":[{"href":"https:\/\/www.icp.universite-paris-saclay.fr\/capri\/wp-json\/wp\/v2\/media?parent=90"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}