Nanocode Patent: Microfluidic Concentration of Biomarkers for UV Fluorescence Detection
Antoine Pallandre (Prof)
Alumni: François-Damien Delapierre (Research Valorization 2021-23)
Nanocode setup positioned on a microscope stage, showing the connections for voltage, pressure, and light. At the top left, the microfluidic chip is shown, and at the bottom right, an image of the specific concentration phenomenon observed by the fluorescence of various biomarkers.
A new concept of microfluidic chip, called Nanocode, has been developed for the pre-concentration of biomarkers, allowing for rapid detection and diagnosis through UV fluorescence imaging. This method offers significant improvements in terms of time efficiency and ease of measurement compared to hospital protocols currently used to detect biomarkers in cerebrospinal fluid (CSF). The valorization of this concept led to the creation of a demonstrator and a market study. The potential medical applications have enabled the integration of this technology within the PROMETHEUS University Hospital Institute (IHU). This IHU aims to propose innovative analytical methods, close to the patient, for sepsis treatment.